EVALUATION OF INFLAMMATORY CYTOKINE AND PLASMA TITANIUM LEVELS IN DENTAL IMPLANT TREATED PATIENTS

Aim: This study aims to evaluate the corrosion properties of Titanium (Ti) dental implants in blood and also, measure the inflamatory cytocine secretion to affect of physiological corrosion on Ti implants. Method: Forty patients were divided to two groups. Group 1 was treated with the Zimmer Tapered ScrewVent implant system which has a Microtextured Ti surface. Group 2 was treated with the Implant Direct ScrewPlant implant system which has a Hydroxy Apatite surface. All implants were inserted in posterior mandibular region. Prior to implantation and 4 months after the surgery, peripheral blood samples were taken and analyzed. Results: The Ti levels of every member in the study group was increased, but not to a statistically significant degree (p>0.05). A comparison of pre- and post-dental implant applications in all study groups showed no differences for levels of serum Ti, IL-6, IL10, or TNF-alpha (p>0.05) except for IL-1 beta (p<0.05). Conclusion: No association was found between serum Ti level and implant application