Fasudil crystal formation IV as well as preparation method and application thereof
2010
The invention particularly relates to a Fasudil crystal formation IV as well as a preparation method and application thereof, belonging to the technical field of medicines. For the Fasudil hydrochloride V crystal formation, Cu-Ka radiation is adopted, and X-ray powder represented by an angle of 2 theta is diffracted by angles of 6.320, 14.240, 14.460, 17.040, 22.640, 22.940, 25.400, 25.700 and 28.100 degrees, wherein the angle of 2 theta has a characteristic peak. The Fasudil hydrochloride crystal formation prepared with the preparation method provided by the invention has the advantages of high physical stability, high purity and the like when being stored and used at normal temperature and is further suitable for industrial production. The invention further discloses the application of the Fasudil hydrochloride in improving and preventing of ischemic cranial vascular diseases caused by various reasons.
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