Quantitative changes in interleukin proteins following focal stroke in the rat.

Abstract The aim of the present study was to quantitate the temporal changes in protein concentration for interleukin (IL)-1α, IL-1β, IL-1ra, and IL-6 from 1 h to 15 days following focal ischemia. Protein expression was evaluated by enzyme-linked immunosorbent assay utilizing newly available rat antibodies. There were no detectable basal levels of IL-1α, 1L-1β, or IL-6 in the sham-operated or non-ischemic control cortex. IL-1β (increased significantly ( P P P P