Vaccine for cocaine dependence: A randomized double-blind placebo-controlled efficacy trial

Thomas R. Kosten,Coreen Domingo,Daryl Shorter,Frank Orson,Charles Green,Eugene Somoza,Rachelle Sekerka,Frances R. Levin,John J. Mariani,Maxine L. Stitzer,D. Andrew Tompkins,John Rotrosen,Vatsal Thakkar,Benjamin Smoak,Kyle M. Kampman

Vaccine for cocaine dependence: A randomized double-blind placebo-controlled efficacy trial

2014

Thomas R. Kosten
Coreen Domingo
Daryl Shorter
Frank Orson
Charles Green
Eugene Somoza
Rachelle Sekerka
Frances R. Levin
John J. Mariani
Maxine L. Stitzer
D. Andrew Tompkins
John Rotrosen
Vatsal Thakkar
Benjamin Smoak
Kyle M. Kampman

Aims We evaluated the immunogenicity, efficacy, and safety of succinylnorcocaine conjugated to cholera toxin B protein as a vaccine for cocaine dependence.

Keywords:

Clinical trial
Anesthesia
Placebo
Cocaine related disorders
Immunogenicity
Cocaine dependence
Immunology
Medicine
Pharmacology
Vaccination
Cholera toxin
double blind
treatment outcome

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