한국산 식물자원으로부터 신생혈관 억제제 검색 ( 1 )

Methanol extracts of 94 Korean plants were screened for angiogenesis inhibitors using the tube-like formation assay of HUVEC (Human Umbilical Vein Endothelial Cell) and evaluated for growth inhibitory activity on A549 cells, human lung cancer cells. Extracts of Euphorbia sieboldiana, Adonis amurensis, and Anthriscus sylvestris showed antiangiogenic and growth inhibitory activity at 50 ㎍/㎖. Aristolochia manshuriens and Styrax obassia expressed antiangiogenic activity without growth inhibitory action.