From a computational point of view: deciphering the molecular synergism between oxidative stress-induced lipid peroxidation products and metabolic dysfunctionality of human liver mitochondrial aldehyde dehydrogenase-2

Emmanuel Adeniji,Fisayo A. Olotu,Letitia Shunmugam,Mahmoud E. S. Soliman

From a computational point of view: deciphering the molecular synergism between oxidative stress-induced lipid peroxidation products and metabolic dysfunctionality of human liver mitochondrial aldehyde dehydrogenase-2

2019

Emmanuel Adeniji
Fisayo A. Olotu
Letitia Shunmugam
Mahmoud E. S. Soliman

ABSTRACTAccumulation of oxidative stress-induced lipid peroxidation products; 4-hydroxynonenal (4HNE) and 4-oxononenal (4ONE), inactivates the metabolic activity of human liver aldehyde dehydrogena...

Keywords:

Human liver
Computational chemistry
Chemistry
Mitochondrial Aldehyde Dehydrogenase
Oxidative stress
Biochemistry
Lipid peroxidation
ALDH2
Acetaldehyde
Enzyme
Oxidative phosphorylation
Aldehyde dehydrogenase
4-Hydroxynonenal
Ethanol metabolism

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