Role of serum magnesium level as an indicator of glycemic control in type 2 diabetes mellitus

Background: Diabetes mellitus (DM) is caused by various etiological factors that lead to different metabolic dysregulations. Magnesium (Mg) is supposed to have some role in glycemic control in Type 2 diabetes and also with the disease progression. This study was taken up to estimate the level of serum Mg and correlate the same with glycated hemoglobin (HbA1c). Aim and Objective: The present study was conducted to estimate serum Mg level in type 2 DM patients and find out if there is any correlation with HbA1c. Materials and Methods: Blood samples from 50 patients of type 2 diabetes were taken and levels of different parameters – fasting blood sugar, postprandial blood sugar, HbA1c, and serum Mg were estimated and analyzed statistically. Results: The mean serum Mg in cases is 1.64 ± 0.15 mg/dl and mean serum Mg in controls is 1.9 ± 0.16 mg/dl. Mean HbA1c in cases is 7.49 ± 1.22% and mean HbA1c in controls is 4.64 ± 0.36%. There is a negative correlation between serum Mg levels and HbA1c. Conclusion: In this study, inverse correlation was found between serum Mg level and HbA1c. Further larger study will be needed to strengthen the results revealed.