Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy

Angela K Peter,Rossi A,Massimo Buvoli,Christopher D Ozeroff,Claudia Crocini,Amy R Perry,Ada Buvoli,Lindsey A. Lee,Leslie A. Leinwand

Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy

2019

Angela K Peter
Rossi A
Massimo Buvoli
Christopher D Ozeroff
Claudia Crocini
Amy R Perry
Ada Buvoli
Lindsey A. Lee
Leslie A. Leinwand

Background In mammals, muscle contraction is controlled by a family of 10 sarcomeric myosin motors. The expression of one of its members, MYH7b, is regulated by alternative splicing, and while the ...

Keywords:

Cardiology
Genetically modified mouse
Myosin
Dilated cardiomyopathy
Internal medicine
Muscle contraction
Cell biology
Alternative splicing
Sarcomeric myosin
Medicine
mammalian heart
Diabetes mellitus
cardiac myocyte

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