Association of Inosine and Cytidine

A rigorous theory for the analysis of an associating system involving two different monomer units, which may also undergo self-association, has been developed. In the present paper the application of the theory to actual data is demonstrated for the first time. The model system chosen is the interaction of inosine with cytidine, both of which self-associate strongly. Application of the theory indicates that inosine associates with cytidine and that the association constant is of a similar order of magnitude to that for the self-association of the monomers.