A Prospective Study of Relationships Between Severity of Liver Disease, PaO 2 Response to 100% Oxygen, and Brain Uptake After 99m Tc MAA Lung Scanning

(48 6 18% vs 25 6 20%; p < 0.04) and lower PaO2 on RA (40 6 7m m Hg vs 576 11 mm Hg; p < 0.001). Conclusion: The degree of hypoxemia associated with HPS was not related to the CP severity of liver disease. HPS patients with additional nonvascular pulmonary abnormalities exhibited lower PaO2 on 100% oxygen. Mortality was associated with lower PaO2 on RA, and with greater brain uptake of 99m Tc MAA. (CHEST 2000; 118:615‐ 624)