SAT0480 ASSESSMENT OF CORONARY ATHEROSCLEROSIS SEVERITY IN MEN WITH CORONARY HEART DISEASE DEPENDING ON BONE MINERAL DENSITY

Background: Objectives: Assess the severity of coronary atherosclerosis in men with coronary heart disease (CHD) depending on bone mineral density (BMD). Methods: 102 of men with verified CHD aged 51-75 (60 .8 ± 6.9) were examined. All patients performed two-energy X-ray absorption of lumbar vertebrae bodies LI-LIV and hip necks (Excell XR-46, Norland, USA) and polyproject coronarangiography (Innova, General Electric, USA). On the basis of results of densitometry on value of T-criterion (the recommendation of ISCD, 2007) estimated BMD condition: normal BMD (T criterion ≥-1), osteopenia (T-criterion from-1 to-2.5) and osteoporosis (OP) (T criterion Results: According to the results of densitometry, patients were found to have 21 patients (20.6%) with normal BMD, 48 (47.0%) - osteopenia and 33 (32.4%) -osteoporosis. Osteopenic syndrome (OPS) was found in 79.4% of men. All patients tested, depending on the degree of CA calcinosis, were distributed as follows: 57.8% of men had pronounced CA calcinosis, 25.5% - increased, 6.9% - moderate, 2.0% - minimal, 7.8% of patients had no CA calcinosis. In a comparative analysis of the degree of coronary calcinosis in men with CHD depending on the T-criterion, it was found that the majority of patients with OPS (69.7% of patients with OP and 60.4% with OPe) had pronounced CA calcinosis. In men with normal BMD, the prevalence of pronounced CA calcinosis (33.3%) was significantly lower than in patients with OPS (p Conclusion: The findings suggest in favor of likely common mechanisms for developing atherosclerosis with OP and allow coronary calcinosis to be considered as a condition potentially increasing the risk of hip fracture. Disclosure of Interests: None declared