Impairment of Monocyte-derived Dendritic Cells in Idiopathic Pulmonary Arterial Hypertension
2009
Background and Aim
With the development of immunology, the role of immune inflammation in idiopathic pulmonary arterial hypertension (IPAH) has attracted interest. Recently, it was discovered that dendritic cells, which are key players in immune inflammation, are implicated in the pathogenesis of IPAH. To elucidate the role of dendritic cells in human IPAH, we compared the changes in the number and immunological function of monocyte-derived dendritic cells (MoDCs) from the peripheral blood of patients with IPAH and healthy controls.
Keywords:
- Inflammation
- Dendritic cell
- Immunology
- Plasmacytoid dendritic cell
- Pathogenesis
- Tumor necrosis factor alpha
- Immune system
- Monocyte
- Pathology
- Biology
- Granulocyte macrophage colony-stimulating factor
- Medical microbiology
- immune inflammation
- Idiopathic Pulmonary Arterial Hypertension
- peripheral blood
- monocyte derived
- Correction
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