A collaborative study of the in-vitro sensitivity to RP 59500 of bacteria isolated in seven hospitals in France

The in-vitro activity of RP 59500 was determined against 1051 recent clinical bacterial isolates. The susceptibility to RP 59500 was determined with an agar dilution technique for all the isolates, while MICs and MBCs were determined for 82 selected strains in broth. Isolates of both Staphylococcus aureus and coagulase-negative staphylococci appeared to be potentially susceptible to RP 59500, independent of susceptibility to methicillin or MLS resistance