Dipeptidyl peptidase IV inhibitory composition derived from bonito
2015
[Problem] To provide a dip stock or a composition derived from bonito stock which has a dipeptidyl peptidase IV (DPPIV) inhibitory action and is highly safe when taken orally. A DPPIV-inhibiting composition derived from or brewed from bonito. A method for producing a dipeptidyl peptidase IV-inhibiting composition derived from soup stock, comprising the following steps: 1) A step of extracting bonito with hot water at 60 ° C. to 100 ° C. and further removing the supernatant by centrifugation to obtain a soup stock; 2) selecting the soup stock from a specific group under optimum conditions A protease derived from at least one strain that is enzymatically degraded by a protease for food industry use, and further obtaining a clarified liquid by centrifugation; 3) a step of purifying the clarified liquid; and 4) an ethanol concentration of 10% , 25%, 50% and 99.5% stepwise gradient elution steps [selection] Figure 1
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