Angina pectoris and slow flow velocity of dye in coronary arteries—A new angiographic finding

The coronary arteriograms of 6 patients with the anginal syndrome revealed a normal coronary arterial tree. This finding was associated with a strikingly slow flow rate of the angiographic dye through the major vessels. This feature is discussed in detail and a theory of small vessel disease is suggested. The purpose of this paper is to bring into focus a new angiographic finding. Its cause is hypothesized and requires clarification by further studies which should include accurate flow measurements, metabolic determinations, and myocardial biopsics.