Comparison of Clinical Efficacy of Ceftiofur to Oxytetracycline for Treatment of Acute Puerperal Metritis in Cows

The objective of this randomized study was to evaluate the efficacy of ceftiofur hydrochloride (Excenel® RTU) administered subcutaneously at the daily dose of 1.0 mg ceftiofur equivalents (CE)/kg body weight (BW) (0.45 mg/lb) for five days for the treatment of acute puerperal metritis in cows in Europe. This treatment was compared to a control of oxytetracycline hydrochloride administered intramuscularly at the daily dose of 10 mg/kg body weight (4.5 mg/lb) for five days, an antibiotic registered for treatment of metritis in Europe.