High tumoral PD-L1 expression and low PD-1+ or CD8+ tumor-infiltrating lymphocytes are predictive of a poor prognosis in primary diffuse large B-cell lymphoma of the central nervous system

Sehui Kim,Soo Jeong Nam,Changhee Park,Dohee Kwon,Jeemin Yim,Seung Geun Song,Chan-Young Ock,Young A Kim,Sung-Hye Park,Tae Min Kim,Yoon-Kyung Jeon

High tumoral PD-L1 expression and low PD-1+ or CD8+ tumor-infiltrating lymphocytes are predictive of a poor prognosis in primary diffuse large B-cell lymphoma of the central nervous system

2019

Sehui Kim
Soo Jeong Nam
Changhee Park
Dohee Kwon
Jeemin Yim
Seung Geun Song
Chan-Young Ock
Young A Kim
Sung-Hye Park
Tae Min Kim
Yoon-Kyung Jeon

ABSTRACTWe investigated the clinicopathological role of the PD-1/PD-L1 pathway in primary diffuse large B-cell lymphoma of the central nervous system (PCNS-DLBCL) arising in the immune-privileged s...

Keywords:

Cancer research
Central nervous system
Diffuse large B-cell lymphoma
CD8
Medicine
Tumor-infiltrating lymphocytes
PD-L1
Lymphoma
Primary central nervous system lymphoma
poor prognosis
pd l1 expression

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