A PRELIMINARY STUDY OF CLINICAL MANIFESTATIONS OF POLYCYSTIC OVARY SYNDROME (PCOS) IN KOLKATA

Women with polycystic ovarian syndrome (PCOS) represent a unique population, with long term implications on fertility, obesity and diabetic complications, which need to be addressed. In our study 80 consecutive PCOS women were screened. The prevalence of various clinical parameters like menstrual irregularities, obesity, hypertension, thyroid problem and diabetes were compared between case-control groups. It was observed that 78.75% PCOS patients had abnormal menstrual cycle. 10% of the PCOS patients were found to be obese whereas in case of control group the percentage were shown is only 3.75%. We found BMI and PCOS were significantly associated (p-value <0.0001). But we did not find any significant association of waist-hip ratio with PCOS (p-value is 0.2120). 25% of the PCOS patients were hypertensive. Thyroid disorder was reported in 25% in PCOS and 2.5% in control group. These PCOS women who were more obese had a significantly higher prevalence of glucose intolerance compared to control women (P= 0.005). The goal of this study was to help improve awareness and discuss the clinical implications of the coexistence of these disorders in this particular patient population.