747TiPSCHEDULING NAB-PACLITAXEL WITH GEMCITABINE (SIEGE): RANDOMISED PHASE II TRIAL TO INVESTIGATE TWO DIFFERENT SCHEDULES OF NAB-PACLITAXEL (ABX) COMBINED WITH GEMCITABINE (GEM) AS FIRST LINE TREATMENT FOR METASTATIC PANCREATIC ADENOCARCINOMA (PDAC)

P. Corrie1, W. Qian2, D.I. Jodrell1, S. Lao-Sirieix3, P. Whittaker3, A. Gopinathan4, A. Chhabra1, K. Dalchau3, B. Basu5, R. Hardy3, J.W. Valle6 Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Cambridge Cancer Trials Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Cambridge Clinical Trials Unit Cancer Theme, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK Department of Oncology, Addenbrooke’s HospitalCambridge University Hospitals NHS Trust, Cambridge, UK Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK