Cancer detection methods

A method of determining the probability that a patient has a particular cancer comprising: (1) analyzing a body fluid sample a panel of genes comprising the APC, EGFR, KRAS, PTEN, and TP53 genes; (2) determine whether each gene of the panel has a mutation; (3) calculating a probability that the patient has one c1 cancer using the formula ** ** Formula wherein the product is taken for all of the mutated genes in the sample (i> = 1, 2, ... panel , n), the sum is taken for all cancers t, M (g | c1) is the frequency of somatic mutations in the gene g in cancer c1, and P0 (c1) is the prior probability of c1 cancer because the patient has cancer.