Genes de Virulencia y Grupo Filogenandeacutetico en Aislados de Escherichia Coli Patogandeacute;nica Aviar
2018
Avian pathogenic Escherichia coli (APEC) shares virulence attributes with strains
of E. coli that cause extraintestinal infections in humans and it is considered that
it could cause a zoonosis; therefore, the objective of this work was to determine
prevalence in a group of APEC isolates of twelve genes associated with virulence
as well as identifying the phylogenetic groups to which they belong. According to
the results it was found that one of the isolates harbors 91.6% of the virulence
genes analyzed and that most of these have between 7 and 8 of these genes.
feoB and iss had the highest prevalence with 95.6% and the genes related to
iron acquisition were present in more than 60% of APEC, while those of the ibeA
invasin and vat toxin were those that were detected with the lowest prevalence
The results showed the great genetic diversity of APEC isolates and suggest that
bacterial systems of iron acquisition, as well as those related to resistance to host are fundamental virulence factors in these bacteria, however, the presence The
rest of the virulence genes is important, since it provides valuable information for
the development of vaccines against avian colibacilosis. It was determined that a
high percentage of APEC belongs to the phylogenetic group B1 group from which
mainly commensal and pathogenic E. coli strains derive, this result strengthens
findings on the evolution of pathogens through the acquisition of virulence genes
through the horizontal route.
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