High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients.

Tilman Schneider-Hohendorf,Andreas Schulte-Mecklenbeck,Patrick Ostkamp,Claudia Janoschka,Marc Pawlitzki,Felix Luessi,Frauke Zipp,Sven G. Meuth,Luisa Klotz,Heinz Wiendl,Catharina C. Gross,Nicholas Schwab

High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients.

2020

Tilman Schneider-Hohendorf
Andreas Schulte-Mecklenbeck
Patrick Ostkamp
Claudia Janoschka
Marc Pawlitzki
Felix Luessi
Frauke Zipp
Sven G. Meuth
Luisa Klotz
Heinz Wiendl
Catharina C. Gross
Nicholas Schwab

Background:Progressive multifocal leukoencephalopathy (PML) can in rare cases occur in natalizumab-treated patients with high serum anti-JCPyV antibodies, hypothetically due to excessive blockade o...

Keywords:

Multiple sclerosis
Progressive multifocal leukoencephalopathy
Cerebrospinal fluid
Blockade
Immunology
Titer
Natalizumab
Medicine
Cell
Antibody

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