Methylation du tRNA dans des cultures de gonades de Carcinus maenas: Inhibition par un extrait purifie des glandes androgenes

Abstract Subcultures of ovaries and testis of the crab Carcinus maenas have been performed in the presence of L-[ Me - 14 C]methionine. Introduction in the medium of a chromatographically-purified liposoluble fraction from the androgenic glands of the same animal inhibits the biological methylation of the tRNA of the ovaries by 62%. The inhibition of methylation of five individual bases varies from 45% to 84%. No inhibition of tRNA methylation is observed under the same conditions with testis subcultures.