Advances in monitoring of cardiovasculardiseases at the point of care
2016
Cardiovascular diseases (CVDs) are the leading cause of death globally.
Most of them are preventable and treatable, which largely depend on
timely and effective diagnosis and interventions. Owing to the rapid
growth of nanotechnology and microfluidics, many portable devices
are developed for monitoring of CVDs at the point-of-care (POC). In
addition, smartphone, as a popular and versatile handheld tool, has
been used not only as a reader for microfluidic assays, but also as
an analyzer for physiological indexes. In this review, we provide
a comprehensive overview of the current status and potential development
of POC diagnostics for CVDs, introduce some commercial POC devices
and developed prototypes, and present the advances in the monitoring
of CVDs based on the smartphone independently or combined with other
devices. We envision that an integrated system based on smartphone
that enables blood testing, disease examination, and imaging will
be the focus of future POC research.
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