Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner

Seyyedeh-Mahla Shavakandi,Mina Ranjbaran,Fatemeh Nabavizadeh,Reyhaneh Vali,Fardin Sehati,Ghorbangol Ashabi

Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner

2021

Seyyedeh-Mahla Shavakandi
Mina Ranjbaran
Fatemeh Nabavizadeh
Reyhaneh Vali
Fardin Sehati
Ghorbangol Ashabi

It has been stated that chronic cerebral hypoperfusion (CCH) markedly prompts neuronal damage and affects cognition. Dimethyl fumarate (DMF), a nuclear erythroid 2-related factor 2 (Nrf2) activator...

Keywords:

Internal medicine
dependent manner
cerebral hypoperfusion
Activator (genetics)
Hippocampus
Apoptosis
neuronal damage
Endocrinology
Ischemia
Dimethyl fumarate
Chemistry

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