Increased Wound-Healing Rate In Pig Skin Treated By Helium-Neon Laser.

We have demonstrated that 11cNc, laws stimulate collagen synthesis both in human stun fibroblast cultures and hairless mice in vivo. Subscqucnt studies on pig skin have also idcntificd the mechanism of the collagen stimulation. Both type 1 and typc 111 procolagcn mRNA, levels were markcdly elevated at day 17 and 26 in wounds treated by laser. Furthermore, typo ill procollagen was cicvatcd in carly stages of wound healing, at day 10, confirming the notion that typc 111 collagen accumulation precedes that of typc 1 in wound healing processes. (for summary,please see table and references below)