Synthesis of 2-(1-Oxo-2,3-Dihydro-1H-Pyrrolizin-2-yl)-2-(Aryl)Acetonitrile Derivatives Via Michael Addition of Trimethylsilyl Cyanide

Several 2-aryl-2-(1-oxo-2,3-dihydro-1H-pyrrolizin-2-yl)acetonitrile derivatives were synthesised by Michael addition of (E)-2-arylidene-2,3-dihydro-1H-pyrrolizin-1-ones with trimethylsilyl cyanide ...