Behavioral Neurochemistry: Application of Neurochemical and Neuropharmacological Techniques to The Study of Operant Behavior

Publisher Summary This chapter focuses on the techniques that permit the simultaneous analysis of behavior and central nervous system activity. The purpose of studying such processes is not necessarily to explain behavior as much as it is to determine the influence that behavior and behavioral variables have on neurochemistry and vice versa. Techniques that yield a more detailed analysis of behavior by providing access to other variables can only extend and clarify basic behavioral processes. Almost all of the methods and approaches necessitate the use of a stereotaxic instrument for precise location and placement of cannulae or probe devices used in the collection of fluid, the injection of a drug, or insertion of a recording electrode into specific brain regions. In addition to basic surgical skills—use of a stereotaxic instrument, or administration and maintenance of anesthesia—animals are monitored much more extensively than is typical or customary in most behavioral studies.