Long-term cardiovascular risk and costs for myocardial infarction survivors in a US commercially insured population

AbstractObjective To quantify clinical and cost long-term outcomes in cardiovascular stable post-myocardial-infarction patients.Research design and methods Subjects with a history of myocardial infarction (MI) who were 50–64 years old and MI- and stroke-free for ≥12 months (index date) were identified in a large US claims database. Individuals were followed for up to 5 years (mean: 2.0 years) after their index date.Main outcome measures Rates of MI, stroke, all-cause death, and a composite of these were analyzed via Cox regression models, adjusted for covariates. Results are reported for the overall population and the subgroups of those with type 2 diabetes, additional prior MI, and non-end-stage renal disease. As a secondary endpoint healthcare costs were evaluated at baseline and during each year of follow-up.Results Over the follow-up period, which averaged 2 years, 7.6% of all 13,492 subjects (10.5% vs. 5.4% with and without the selected risk factors, respectively) experienced at least one of the outc...