Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives

Rosaria Gitto,Laura De Luca,Francesca Mancuso,Sonia Del Prete,Daniela Vullo,Claudiu T. Supuran,Clemente Capasso

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives

2019

Rosaria Gitto
Laura De Luca
Francesca Mancuso
Sonia Del Prete
Daniela Vullo
Claudiu T. Supuran
Clemente Capasso

AbstractA series of sixteen benzenesulfonamide derivatives has been synthesised and tested as inhibitors of Vibrio cholerae carbonic anhydrase (CA) enzymes, belonging to α-CA, β-CA, and γ-CA classe...

Keywords:

Vibrio cholera
Biochemistry
Docking (molecular)
Chemistry
Vibrio cholerae
Carbonic anhydrase
Cholera
Enzyme
therapeutic treatment

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