Correlation between chronic obstructive pulmonary disease and lung cancer

Objective To study the correlation between chronic obstructive pulmonary disease (COPD) and lung cancer. Methods Two huandred and ten lung cancer patients collected in our hospital from November 2010 to November 2013 were regarded as experimental group, and 226 healthy people without any cancer collected in the center of healthy physical of our hospita at the same time were regarded as control group, to observe the relationship between the two factors (such as the history of personal respiratory disease, family history of respiratory disease) and lung cancer, then to compare the rate of COPD between smoking patients and not smoking patients in two groups. Results Among the respiratory system diseases, pneumonia and asthma were no significant related lung cancer (all P>0.05); the patients sufferring from COPD, bronchitis, emphysema, pulmonarytuberculosis, increasedsignificantly the risk of lung cancer (all P<0.05), the relationship between COPD and lung cancer was highest (OR=2.73). People with family history of COPD and lung cancer, had a significant increase in the risk of lung cancer (P<0.05). The rate of COPD among smoking patients of experimental group was significantly higher than the control group (χ2=5.482, P<0.05). The rate of COPD among not-smoking patients of experimental group was significantly higher than control group (χ2=5.901, P<0.05). Conclusions Patients with COPD or a family history with COPD, will increase the risk of lung cancer, and whether or not to smoke, COPD will still increase the risk of lung cancer. Key words: Chronic obstructive pulmonary disease; Lung cancer