Determination of 5-HT3 Receptor Antagonists in Human Urine by Porous Graphitic Carbon (PGC) Solid Phase Extraction (SPE) Coupled with High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS)

Fanfan Ye,Huihui Wan,Hua Zhang

Determination of 5-HT3 Receptor Antagonists in Human Urine by Porous Graphitic Carbon (PGC) Solid Phase Extraction (SPE) Coupled with High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS)

2020

Fanfan Ye
Huihui Wan
Hua Zhang

The quantitative determination of drugs in urine by high performance liquid chromatography electrospray-ionization mass spectrometry (HPLC-ESI-MS) is challenging due to complex matrix interferences...

Keywords:

Tandem mass spectrometry
hplc ms ms
Chemistry
Urine
Porosity
Solid phase extraction
Mass spectrometry
5-HT3 receptor
Chromatography
High-performance liquid chromatography

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