Cartilage metabolism and mechanobioscience.
2016
: Joint cartilage is under exposure to repetitive mechanical stress. It is well known fact that the mechanical stress is a major cause of joint disorders such as osteoarthritis. However the molecular mechanisms of cartilage under mechanical stress remain unclear. In recent years, some notable mechanosensor or signal cascades relating to mechanotransduction had been identified, which might be promising targets for treatment of joint disorders.
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