Functional analysis of a novel SCN5A mutation G1712C identified in Brugada syndrome

OBJECTIVE: To elucidate the molecular and electrophysiological mechanisms of Brugada syndrome through functional analysis of a novel SCN5A gene mutation G1712C. METHODS: A recombinant plasmid pRc

Keywords:

• HEK 293 cells
• Mutant
• Transfection
• Protein subunit
• Molecular biology
• Mutagenesis
• Biology
• Mutation
• Cardiac muscle cell
• Sodium channel

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