Creatinine clearnce Rate (CCR) in Dignosing Different stages of chronic kidney Disease (CKD) - An update and review

on either side of the aorta and inferior vena cava. Each kidney contains 1 million functional units, or ‘nephrons’. These consists of glomerulus’s (where filtration of plasma occurs), proximal convoluted tubule, loop of Henle and distal convoluted tubule (where selective reabsorption of fluid and solutes from the filtrate occurs), and the collecting duct. The collecting ducts of multiple nephrons drain into the renal pelvis and ureter. There is a rich blood supply (20% - 25% of cardiac output). Intralobular branches of the renal artery give rise to the glomerular afferent arterioles which supply the capillaries within the glomerulus. The efferent arteriole, leading from the glomerulus, supplies the distal nephron and medulla in a ‘portal’ circulation. Glomeruli 7