[Adenosine triphosphatases in the bovine endometrium and in the trophoblast during implantation. Microscopic and electron microscopic investigations (author's transl)].
1977
Investigations of the bovine epithelium uteri and trophoblast between the 22nd and 24th day after insemination have been made according to the method of FARQUHAR and PALADE (1966) concerning the activity and microstructural localization of the Mg++-, Ca++- as well as the (Mg++-Na+-K+)-ATPases which may be made active (E. C. 3.6.1.3). The evidence of the ATPases in the so-called free cells during the pre-implantative stage is associated with a production of immunoglobulin A and thus the importance of these cells within the scope of an immunological position of reaction of the endometrium is being discussed. On the epithelium uteri there is a correlation at first between the activity of this hydrolase, which can only be proved at the later pre-contact stage, and the microstructural symptoms of increasing secretion. During the subsequent stage of apposition and after consolidated implantation ATPase-dependent transportations through membranes are likely to serve in the formation of hemotrophs as well as in the hemotroph metabolism. Finally, an attempt is made to give an explanation of the precipitate depositions on the cells of the uterine glands.
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