Experimental study on the regulation of erlotinib-induced radiosensitization with an anti-c-MET monoclonal antibody.

Hong Qing Zhuang,Hongxia Zhuang,Qifu Bo,Yihang Guo,Jun Wang,Lu Jun Zhao,Z. Yuan,Ping Wang

Experimental study on the regulation of erlotinib-induced radiosensitization with an anti-c-MET monoclonal antibody.

2014

Hong Qing Zhuang
Hongxia Zhuang
Qifu Bo
Yihang Guo
Jun Wang
Lu Jun Zhao
Z. Yuan
Ping Wang

Purpose Erlotinib is a novel therapeutic agent for cancer treatment. This study was performed to investigate the role of c-MET-PI3K-AKT pathway in the regulation of erlotinib-induced radiosensitization.

Keywords:

Cancer research
Immunology
Erlotinib
C-Met
Cancer
PI3K/AKT/mTOR pathway
Monoclonal antibody
Tyrosine-kinase inhibitor
Medicine
cancer treatment

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