Psychometric evaluation of Global Evaluation of Treatment Effectiveness: a tool to assess patients with moderate-to-severe allergic asthma

SummaryRecent trials of treatment for patients with moderate to severe allergic (immunoglobulin E-mediated) asthma have included a Global Evaluation of Treatment Effectiveness (GETE), which is completed by both the patient and the physician. The current analyses were designed to explore some psychometric properties of this measure using secondary analysis of trial data.The results found some evidence to support the psychometric properties of the measure, and some evidence that was more equivocal. The GETE had low to moderate rates of missing data. There was also a high level of agreement between the two measures. The five levels of the GETE were significantly differentiated in terms of symptom scores, use of rescue medication and forced expiratory volume (physician version only), and health-related quality of life (Asthma Quality of Life Questionnaire).The GETE is a simple measure of perceived treatment effectiveness that reflects clinical outcomes and health-related quality of life, and is not burdensome...