Pyrrolidinone and Piperidinone Isocyanides from Isocyano Esters
2014
The alkylation of isocyano esters with 1,2- and 1,3-dibromoalkanes affords bromo isocyanides. Under treatment with various amines the latter form new isocyano-substituted lactams, which can be further used in Passerini or Ugi reactions.
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