Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial

Thiago Gonçalves dos Santos Martins,Ana Luiza Fontes de Azevedo Costa,Karina Mie Furuzawa,Roger Chammas,Milton Ruiz-Alves

Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial

2019

Thiago Gonçalves dos Santos Martins
Ana Luiza Fontes de Azevedo Costa
Karina Mie Furuzawa
Roger Chammas
Milton Ruiz-Alves

Purpose To evaluate the influence of preoperative mitomycin C (MMC) on the proliferative behavior of fibroblasts and fibrovascular tissue derived from the primary pterygium using the immunohistochemical method (Ki67 and CD34).

Keywords:

Mitomycin C
Urology
CD34
Randomized controlled trial
Immunohistochemistry
Surgery
Diabetes mellitus
Medicine
Subconjunctival injection
Proliferation index
Pterygium excision
pterygium surgery
antiangiogenic effect

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