Article originalDépistage de la trisomie 21 par le test combiné du premier trimestre suivi par l'échographie du second trimestre en population généraleScreening for Down Syndrome using first-trimester combined screening followed by second trimester ultrasound examination in an unselected population☆
2007
Background
Recent studies have reported the efficacy of first trimester combined screening for Down Syndrome based on maternal age, serum markers (human chorionic gonadotropin, pregnancy-associated plasma protein A), and ultrasound measurement of fetal nuchal translucency. However, those do not incorporate the value of the widely accepted routine 20–22 week anomaly scan.
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