Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

Zobia Umair,Santosh Kumar,Khezina Rafiq,Vijay Kumar,Zia Ur Reman,Seung-Hwan Lee,Sung Chan Kim,Jae-Yong Lee,Unjoo Lee,Jaebong Kim

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

2020

Zobia Umair
Santosh Kumar
Khezina Rafiq
Vijay Kumar
Zia Ur Reman
Seung-Hwan Lee
Sung Chan Kim
Jae-Yong Lee
Unjoo Lee
Jaebong Kim

Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicate...

Keywords:

Transforming growth factor
MAPK/ERK pathway
Fibroblast growth factor
Endoderm
Xenopus
Cell biology
Germ layer
Chemistry
Embryo
Mesoderm

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