Training health workers for magnesium sulfate use reduces case fatality from eclampsia: results from a multicenter trial
2013
Objective
To investigate the effectiveness of an intervention aimed at improving the case management of eclampsia.
Design
A multi-center intervention study.
Setting
Six teaching hospitals in Nigeria.
Sample
Clinical records of cases of eclampsia treated before and 1 year after the intervention.
Methods
Doctors and midwives in selected hospitals were re-trained to manage eclampsia using magnesium sulfate according to the Pritchard protocol.
Main outcome measures
Eclampsia case fatality rates, maternal and perinatal mortality rates before and after the intervention.
Results
A total of 219 cases of eclampsia were managed over a 12-month period. There were seven maternal deaths. The post intervention case fatality rate of 3.2% was significantly less than the pre-intervention rate of 15.1% (p 0.05).
Conclusion
An intervention to build the capacity of care-providers to use an evidence-based protocol for the treatment of eclampsia in Nigeria was successful in reducing associated case fatality rate. The increased and widespread use of such an intervention in maternity units might contribute to the reduction of maternal mortality in low-income countries.
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