Spontaneous Resistance to Chloroquine in a Strain of Rodent Malaria (Plasmodium berghei yoelii)
1967
DURING an, investigation of sporozoite induced, infections of Plasmodium berghei yoelii in mice, chloroquine was given in an attempt to eliminate the erythrocytic stages of the parasite. Unexpectedly, the parasite failed to respond to the drug.
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