Oligomeric flavanoids. Part 24. Controlled biomimetic synthesis of profisetinidin triflavanoid related phlobatannins

Abstract The complex structures of the economically important group of profisetinidin triflavanoid related phlobatannins are synthetically accessable in a controlled biomimetic fashion via the repetitive formation of the interflavanyl bond and pyran ring rearrangement of the chain extender unit under mild alkaline conditions. The repetitive formation of the interflavanyl bond and pyran ring rearrangement of the chain extender unit permit controlled synthetic access to phlobatannins at the ‘trimeric’ level Download full-size image