THE CRYSTAL STRUCTURE OF DIBROMO (PHENYL-2-PYRIDYL DIMETHYLHYDRAZONE)PALLADIUM(II)

Abstract Nitrogen-containing heterocyclic compounds play an important role in several biological processes. Furthermore, their biological activity seems often to depend upon interaction with a metal ion. Interest in the study of hydrazones and their metal complexes has been growing because of their physiological activity, coordination capability and application in analytical chemistry.1,2 Many hydrazones and their metallic derivatives show very interesting biological activity, e.g., as antitumour or anticonvulsant agents, and behave as cytotoxic compounds toward tumour cells.3 During the past few years, in addition to platinum compounds, coordination compounds of palladium(II) and (IV) seem to be promising in cancer chemotherapy.4 Due to the biological activity of heterocyclic hydrazones and in continuing our systematic investigations of the platinum group metals with hydrazones and generally with heterocyclic nitrogen donor ligands,5–10 we report here the crystal structure of dibromo(phenyl-2-pyridyldime...