A new efficient synthesis of N-(2-(2-(3-methoxy-4-(oxazol-5-yl)phenylamino)oxazol-5-yl)phenyl)-N-methyl-2-morpholinoacetamide (BMS-337197), A novel IMPDH inhibitor
2007
A new, efficient method has been developed for the synthesis of BMS-337197, a novel IMPDH inhibitor. The new method uses the readily available 2-bromo-1-(2-nitrophenyl)ethanone as a starting reagent and provides BMS-337197 in 9 steps in 55% overall yield on a multigram scale.
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