Synthesis of Dipeptidyl Peptidase-4 Inhibitors: A Brief Overview

Abbreviations: T2DM, Type 2 Diabetes Mellitus; throughput screening; DIAD, diisopropyl azodicarbox HOBT, Hydroxybenzotriazole; Dde, 1-(4,4-dimethyl Isopropyl alcohol; DMAP, Dimethyl aminopyridine; DM Lithiumaluminiumchloride; PDH/FDH enzyme, pyruv methyluronium tetrafluoroborate; PS Carbodidimide stensulphidechloride; MTBE, methyl-tert-butylether; H N,N0 ,N0-tetramethyluronium hexafluorophosphate; Li DIPA, Diisopropyl amine; DIC, N,N0-diisopropylcarbod