Is there a dose–response relationship of metformin treatment in patients with polycystic ovary syndrome? Results from a multicentric study

A.M. Fulghesu1, D. Romualdi2,*, C. Di Florio2, S. Sanna1, V. Tagliaferri2, A. Gambineri3, F. Tomassoni3, L. Minerba4, R. Pasquali3, and A. Lanzone2,5 Department of Obstetrics and Gynaecology, Universita di Cagliari, Cagliari, Italy Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Largo ‘A. Gemelli’ 8, Rome 00168, Italy Division of Endocrinology, Department of Clinical Medicine, University Alma Mater Studiorum, S. Orsola-Malpighi Hospital, Bologna, Italy Department of Public Health, Universita degli studi di Cagliari, Cagliari, Italy OASI Institute for Research, Troina, Italy