스테로이드성 주사 환자 66예의 임상적 고찰

Background: Topical corticosteroids are not uncommonly abused in patients with facial dermatoses. Although it iswell known that uncontrolled use of topical corticosteroids cause steroid-induced rosacea, its clinical manifestation isnot studied yet in Korean patients.Objective: The purpose of this epidemiological study was to investigate a usage history of topical corticosteroid andclinical manifestation of steroid-induced rosacea.Methods: Among the 424 rosacea patients who visited the dermatologic clinics of Pusan National University Hospitalbetween January 2006 and May 2011, a face-to-face structured questionnaire was given to 66 rosacea patients witha history of topical corticosteroid use on the face for more than 1 month before onset of rosacea symptoms.Investigated factors include sex, age, history about use of topical corticosteroids and clinical manifestations.Results: Of the 66 patients, 41 were female and 25 were male with the mean age of 52.1±14.6 (range 16∼76)year. Celestone-G(R)(n=14) was the most commonly used product in the 34 patients who remembered the brandname of topical corticosteroids, which they had used. Forty-three patients used topical corticosteroids for treatmentof facial skin lesions without diagnosis. Eighteen patients purchased topical corticosteroids without doctor`sprescription. The mean duration and frequency of topical corticosteroid use was 3.8 years and 1.3 times per day,respectively. Constant erythema (n=31) was the most common symptom and it started to occur 2 months after useof topical corticosteroid.Conclusion: High-potency topical corticosteroids are frequently used for patients with facial dermatoses withoutcorrect diagnosis and without doctor`s prescription. Besides, abuse of topical corticosteroids cause rosacea symptoms,such as constant erythema. To prevent the occurrence of steroid-induced rosacea, there should be a great socialconcern for abuse and misuse of topical corticosteroid in patients with facial dermatosis. (Korean J Dermatol2012;50(12):1036∼1041)